Non ed version of sildenafil citrate5/29/2023 ![]() Many of the 979 participants (mean age, 58 years mean ED duration, 4.5 years) had concomitant hypertension (28%), diabetes (22%), or hyperlipidemia (14%). Adverse events that were serious or led to dosing changes or discontinuation (temporary or permanent) were recorded. ![]() ![]() Men with ED who had previously completed 1 of 4 double-blind trials with short-term open-label extension (combined duration, 0.9–1.2 years) were eligible for this 4-year, open-label, extension study, which assessed the safety and effectiveness of flexible doses (25, 50, and 100 mg sildenafil) used as needed. ![]() Because sildenafil citrate is a treatment, not a cure, for erectile dysfunction (ED), many men may choose to use it for an extended period.
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